Analysis and characterization of sulfane sulfur
1Department of Analytical Biochemistry, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.
Analytical Biochemistry
|January 5, 2024
Summary
Sulfane sulfur, or bound sulfur, refers to sulfur atoms linked to other sulfur atoms, including persulfides and polysulfides. This review details methods for measuring these compounds, crucial for understanding hydrogen sulfide
Area of Science:
- Biochemistry
- Analytical Chemistry
Background:
- The definition of sulfane sulfur evolved from vague
- bound sulfur
- to encompass species like persulfides and polysulfides relevant to hydrogen sulfide biology.
Approach:
- This review synthesizes methods for quantifying sulfane sulfur, including historical cyanolysis and modern techniques.
- It covers diverse analytical approaches such as chromatography, mass spectrometry, and fluorescent probes.
Key Points:
- Persulfides and polysulfides, forms of bound sulfur, are implicated in biological effects attributed to hydrogen sulfide.
- Quantitative determination of sulfane sulfur has advanced significantly from early cyanolysis methods.
- Current detection methods encompass colorimetric assays, electrochemical sensors, various chromatography techniques, and specialized probes.
Conclusions:
- A comprehensive understanding of sulfane sulfur measurement is essential for advancing research in hydrogen sulfide biology.
- The review provides an overview of established and emerging methodologies for sulfane sulfur detection.
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