Related Experiment Video
Updated: Jul 5, 2025
04:56
Laryngeal Mask Airway LMA Placement in a Neonatal Patient Simulator Using a Non-Inflatable Supraglottic Airway SGA
Published on: July 14, 2023
2.9K
Peri-extubation settings in preterm neonates: a systematic review and meta-analysis
Yogesha K Nagaraj1, Said Al Balushi2, Courtney Robb3
1Department of Pediatrics, McMaster University, Hamilton, ON, Canada.
Summary
Higher continuous positive airway pressure (CPAP) may reduce extubation failure in preterm neonates. Further research is needed to optimize peri-extubation settings for improved clinical outcomes.
Area of Science:
- Neonatal respiratory support
- Clinical practice guidelines
- Evidence-based medicine
Background:
- Preterm neonates often require mechanical ventilation and subsequent extubation.
- Optimizing peri-extubation settings is crucial for successful respiratory support weaning.
- Current evidence on optimal settings and their impact on outcomes requires systematic synthesis.
Approach:
- Systematic review and meta-analysis of existing literature.
- Inclusion criteria focused on peri-extubation settings and clinical outcomes in preterm infants.
- Random-effects models were employed for data synthesis where appropriate.
Key Points:
- Pooled analysis summarized peri-extubation settings across included studies.
- Higher continuous positive airway pressure (CPAP) levels were associated with reduced treatment failure (OR 0.46, 95% CI 0.27-0.76).
- No significant association was found between higher CPAP and re-intubation rates (OR 0.66, 95% CI 0.22-1.97).
Conclusions:
- Peri-extubation settings data can inform clinical decision-making.
- Higher CPAP may be beneficial in reducing extubation failure in preterm neonates.
- More research is necessary to identify peri-extubation strategies that optimize neonatal outcomes.
More Related Videos
05:50International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure
Published on: March 12, 2020
13.6K
03:58Author Spotlight: Advancing Awake Nasotracheal Intubation with Flexible Video Rhino-Laryngoscopes
Published on: August 2, 2024
712
Related Concept Videos
01:24Endotracheal Tube Extubation
694
Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals....
694
01:17Endotracheal Intubation II: Nursing Management
667
Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
667
01:15Endotracheal Intubation I: Procedure
1.3K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
1.3K
01:29Mechanical Ventilation I: Indication and Settings
382
Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
382
01:21Tracheostomy Decannulation
176
Tracheostomy decannulation is a significant milestone in the liberation of mechanically ventilated patients. Despite its importance, there is no universally accepted protocol for this procedure. This demands an evidence-based, individualized approach.
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
Description of the Procedure
Decannulation refers to the permanent removal of the tracheostomy tube, signaling the resolution of the condition that initially necessitated the tracheostomy. The process requires a well-coordinated interplay between...
176
01:26Endoscopic Studies II: Thoracocentesis
264
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
264