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Updated: Jul 6, 2026

Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
[Position statement for improvement in reperfusion of ST-elevation myocardial infarction in Latin America]
Juan P Costabel1, Miguel Quintana2, Joaquín Perea3
1Unidad Coronaria, Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina.
Insights
Timely ST-segment elevation myocardial infarction treatment, prioritizing primary percutaneous coronary intervention, improves outcomes. When unavailable, fibrinolysis with rescue angioplasty or a pharmacoinvasive strategy are effective alternatives.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- ST-segment elevation myocardial infarction (STEMI) treatment varies geographically.
- Primary percutaneous coronary intervention (PCI) is the preferred reperfusion strategy for STEMI when timely and operator-dependent.
- Geographic barriers and operator experience significantly impact STEMI treatment accessibility and efficacy.
Abstract:
The treatment of ST-segment elevation myocardial infarction has barriers depending on the geographic region. Primary coronary angioplasty is the treatment of choice, if it is performed on time and by experienced operators. However, when it is not available, the administration of fibrinolysis and referral for rescue angioplasty, in case of negative reperfusion, is the best strategy. In the same way, coronary angioplasty, as part of a pharmacoinvasive strategy, is the best alternative when there is positive reperfusion. The development of infarct treatment networks increases the number of patients reperfused within the recommended times and improves outcomes. In Latin America, national myocardial infarction treatment programs should focus on improving outcomes, and long-term success depends on working toward defined goals and enhancing functionality, therefore programs should develop capacity to measure their performance. The following document discusses all of these alternatives and suggests opportunities for improvement.
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