The ACTIV-6 Stakeholder Advisory Committee: a model for virtual engagement in decentralized clinical trials
Megan E Hamm1, Jonathan Arnold1, Josh Denson2
1Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Journal of Clinical and Translational Science
|January 17, 2024
Summary
Patient and caregiver engagement is crucial for patient-centered research. A remote model using Zoom and blogs effectively engaged stakeholders in the ACTIV-6 decentralized trial, offering insights for future research partnerships.
Area of Science:
- Patient-centered research
- Clinical trial management
- Stakeholder engagement
Background:
- Patient and caregiver engagement is vital for ensuring research relevance and participant satisfaction.
- Traditional face-to-face engagement methods face challenges in decentralized trials.
- Lived expertise enhances research transparency and dissemination.
Purpose of the Study:
- To describe a remote stakeholder engagement model for decentralized trials.
- To evaluate the impact of patient, caregiver, and clinician partnership in the ACTIV-6 trial.
- To provide recommendations for future remote engagement strategies.
Main Methods:
- Utilized a remote model for stakeholder engagement, including Zoom meetings and blog communications.
- Focused on research partnership with patients, caregivers, and clinicians.
- Applied engagement strategies within the context of the ACTIV-6 decentralized trial.
Main Results:
- Successfully engaged diverse stakeholders remotely in the planning and oversight of the ACTIV-6 trial.
- Demonstrated the feasibility and impact of a remote engagement approach.
- Collected insights and suggestions for improving future remote engagement practices.
Conclusions:
- The remote engagement model employed in the ACTIV-6 trial provides a viable strategy for decentralized research.
- Experiences from ACTIV-6 can inform best practices for engaging stakeholders in future decentralized trials.
- Remote engagement facilitates broader participation and enhances patient-centeredness in clinical research.
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