A CASE REPORT OF EOSINOPHILIC GRANULOMATOSIS WITH POLYANGIITIS

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Charg-Strauss syndrome or allergic granulomatous angiitis, is defined as a systemic vasculitis identified by the presence of allergic rhinitis and/or asthma, correlated with the presence of marked eosinophilia in the peripheral blood, eosinophilic infiltration of various organs with extensive areas of necrosis, eosinophilic, giant cell vasculitis of vessels of small and medium caliber, as well as perivascular and interstitial necrotizing granulomas. The frequency is 10 - 14 cases per million in the adult population. The average time interval from the onset of the disease to establishing the diagnosis is 49.7 (±6.1) months. Knowledge of the diagnostic criteria and features of the course of EGPA is necessary for early diagnosis and timely initiation of protocolic treatment. This article presents a clinical case of atypical EGPA without existing asthma and with atypical immunological changes.