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Allergen sensitization study in Dongying, China: An epidemiological study
Yingying Zhang1, Mei Shang, Ying Tian
1Department of Pediatrics, Shengli Oilfield Central Hospital, Dongying City, Shandong Province, China.
Medicine
|January 19, 2024
Summary
Egg allergy is most common in Dongying, China, with significant correlations found between various pollen and food allergens. This study improves understanding and management of localized allergic diseases.
Area of Science:
- Allergy and Immunology
- Environmental Health
- Clinical Medicine
Background:
- Investigating specific immunoglobulin E (IgE) levels to common allergens in patients with localized allergic diseases in Dongying, China.
- Analyzing the interconnections between pollen and food allergen sensitization patterns.
Purpose of the Study:
- To determine the prevalence of specific IgE sensitization to various allergens in a Chinese population.
- To identify correlations between different allergen sensitizations.
- To provide insights for clinical diagnosis and prevention of allergic diseases.
Main Methods:
- Blood samples from 230 allergic patients (January 2022-January 2023) were analyzed for specific IgE levels using the Fobock platform.
- Statistical analysis included chi-square tests for gender and age relevance.
- SPSS 25.0 statistical software was utilized for data analysis.
Main Results:
- Eggs were the most common sensitizing allergen, followed by dust mites. Cypress and mango were least sensitizing.
- Male patients showed higher sensitivity to cottonwood and eggs; children (0-10 years) had heightened sensitivity to multiple allergens.
- Strong correlations were observed between allergens, notably Birch Tree and Cottonwood (0.88), Cottonwood and Pine Tree (0.86), and Birch Tree and Pine Tree (0.84).
Conclusions:
- Egg sensitization is highly prevalent in the Dongying area.
- Significant correlations exist between various pollen and food allergens, suggesting cross-reactivity.
- Findings enhance understanding of allergic disease mechanisms and inform clinical management strategies.
