[Translated article] Medical Devices in Patients With Diabetes and Contact Dermatitis.

Area of Science:

• Dermatology
• Allergology
• Medical Device Technology

Background:

• Continuous glucose monitors (CGMs) and insulin pumps have transformed diabetes management.
• Increasing reports link these devices to contact dermatitis, necessitating allergen identification.
• Key allergens identified include isobornyl acrylate, colophony, and abietic acid derivatives.

Purpose of the Study:

• To identify allergens causing contact dermatitis in users of diabetes management devices.
• To inform dermatologists and endocrinologists about potential skin reactions and management strategies.
• To encourage collaboration between clinicians and device manufacturers for improved patient outcomes.

Main Methods:

• Literature review and clinical case analysis of contact dermatitis associated with diabetes devices.
• Identification of specific chemical sensitizers present in device adhesives and components.
• Review of current and emerging allergens in diabetes technology.

Main Results:

• Isobornyl acrylate identified as a primary allergen in FreeStyle glucose sensors, leading to its removal.
• Colophony and abietic acid derivatives confirmed as common sensitizing agents in adhesives.
• New allergens like dipropylene glycol diacrylate are under investigation.

Conclusions:

• Diabetes device allergens can cause significant adverse skin reactions, impacting device adherence and quality of life.
• Dermatologists play a vital role in managing contact dermatitis and advising on alternative solutions.
• Collaboration with manufacturers is essential for developing safer diabetes management technologies.