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Hydrogels and Wound Healing: Current and Future Prospects.
Varshan Gounden1, Moganavelli Singh1
1Nano-Gene and Drug Delivery Laboratory, Discipline of Biochemistry, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
Gels (Basel, Switzerland)
|January 22, 2024
Summary
Hydrogels offer advanced wound healing solutions by maintaining a moist environment and absorbing exudates. This review explores natural and synthetic hydrogels, highlighting their potential to overcome limitations of traditional wound care methods.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Wound Care Technology
Background:
- Chronic wound care presents significant socioeconomic burdens due to infections and prolonged healing times.
- Current treatments like surgery and dry dressings have limitations, including pain and lack of healing promotion.
- Hydrogels are promising due to their ability to create a moist wound environment, absorb exudates, and incorporate therapeutic agents.
Purpose of the Study:
- To review natural and synthetic hydrogels for wound healing applications.
- To discuss recent advancements in hydrogel technology for wound management.
- To explore alternative approaches in wound healing beyond conventional methods.
Main Methods:
- Comprehensive literature review utilizing Scopus, PubMed, Science Direct, and Web of Science databases.
- Focus on research published over the last fifteen years.
- Analysis of natural and synthetic hydrogel properties and applications in wound healing.
Main Results:
- Hydrogels provide a moist healing environment, absorb wound exudates, and offer adaptability.
- Hydrogels can be engineered to deliver active compounds like growth factors and antimicrobials.
- Recent advancements show significant potential for hydrogels in improving wound healing outcomes.
Conclusions:
- Hydrogels represent a significant advancement over traditional wound dressings.
- Further research into hydrogel technology can lead to improved treatments for acute and chronic wounds.
- Hydrogels offer a versatile platform for developing next-generation wound care solutions.
