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Updated: Jul 5, 2025

Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling
Published on: June 23, 2022
Predictors of later COVID-19 test seeking
Amal Ga'al1, Abby Kapsack1, Abdalla Mahmud2
1Faculty of Medicine, University of Toronto, Toronto, Canada.
Delays in COVID-19 testing are common, with older age and certain symptoms like dyspnea linked to later seeking. Encouraging earlier testing is crucial to minimize disease transmission.
Area of Science:
- Public Health
- Infectious Disease Epidemiology
- Healthcare Management
Background:
- Delayed COVID-19 testing increases household and community transmission risks.
- Limited understanding exists regarding patient characteristics and symptoms associated with delayed SARS-CoV-2 test seeking.
Purpose of the Study:
- To identify patient characteristics and symptom profiles associated with delayed COVID-19 testing.
- To inform strategies for encouraging timely SARS-CoV-2 testing.
Main Methods:
- Retrospective cohort study of symptomatic COVID-19 patients in a virtual care program (March 2020 - June 2021).
- Primary outcome: testing more than 3 days from symptom onset.
- Multivariable logistic regression analyzed predictors including patient demographics and 30 individual symptoms or 7 symptom clusters.
Main Results:
- Nearly half (46.8%) of eligible patients underwent later testing.
- Older age and recent travel history were associated with increased odds of late testing.
- Cardiorespiratory, gastrointestinal, neurological, and psychiatric symptoms were linked to delayed testing; specific symptoms like dyspnea and anosmia also correlated with later testing.
Conclusions:
- Specific patient demographics and symptom clusters predict delayed COVID-19 testing.
- Targeted interventions are needed to promote earlier testing and reduce transmission.
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