Related Experiment Video
Updated: Jul 4, 2025
10:17
Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
Published on: January 8, 2018
13.2K
Imaging Genomics and Multiomics: A Guide for Beginners Starting Radiomics-Based Research
Shiva Singh1, Bahram Mohajer2, Shane A Wells3
1Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland.
Academic Radiology
|January 29, 2024
Summary
Radiomics, the analysis of medical images for hidden data, aids in tumor detection and prognosis prediction. This guide clarifies radiomics workflows and research expectations for improved medical care.
Area of Science:
- Radiology
- Medical Imaging
- Computational Biology
Background:
- Radiomics extracts quantitative features from medical images using advanced algorithms.
- It aims to identify imaging biomarkers for improved tumor detection, prognosis, and treatment response assessment.
- Radiogenomics links imaging features with gene expression profiles, offering deeper biological insights.
Purpose of the Study:
- To describe the radiomics workflow.
- To provide guidance for initiating radiomics-based research projects.
- To address the lack of consensus on optimal radiomics methodologies.
Main Methods:
- Utilizes advanced mathematical analysis of pixel-level image data.
- Extracts quantitative features beyond traditional imaging interpretation.
- Integrates radiomics with genomics in the emerging field of radiogenomics.
Main Results:
- Radiomics enhances medical imaging by providing data for diagnosis, disease management, and prognostication.
- Identified imaging biomarkers can predict patient prognosis and treatment response.
- Radiogenomics research is expanding, investigating correlations between imaging phenotypes and genotypes.
Conclusions:
- Radiomics offers a powerful approach to leverage complex image data for clinical decision-making.
- Standardization of radiomics methods is needed to ensure reliable and reproducible research.
- Further research in radiomics and radiogenomics promises to advance precision medicine.
More Related Videos
07:13Author Spotlight: An Efficient and Robust Software for Automated Fusion of Multiple Preclinical Imaging Modalities
Published on: October 27, 2023
1.1K
02:09Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
598
Related Concept Videos
02:02Genomics
36.3K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.3K
01:30Radiological Investigation I: X-ray and CT
239
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
239
01:24Magnetic Resonance Imaging
5.2K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.2K
01:29Positron Emission Tomography
4.2K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
4.2K
01:24X-ray Imaging
5.5K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.5K
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
122
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
122