Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Methods Of Healthcare Delivery System

Methods Of Healthcare Delivery System

At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...

Lymphatic Vessels and Lymph Transport

Lymphatic Vessels and Lymph Transport

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular...

Two-Compartment Open Model: Extravascular Administration

Two-Compartment Open Model: Extravascular Administration

The two-compartment model for extravascular administration represents a drug's absorption and distribution process. It features a central compartment, where the drug is first absorbed, and a peripheral compartment, which illustrates the drug's distribution throughout the body. The rate of change in drug concentration in the central compartment is calculated by three exponents: absorption, distribution, and elimination.
The absorption exponent (ka) indicates the speed at which the drug...

Gas Exchange and Transport

Gas Exchange and Transport

Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Motor Unit Stimulation

Motor Unit Stimulation

When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Renal Function Decline After Vascularized Composite Allotransplantation.

Transplantation direct·2026

Same author

In Vitro hRPTEC TERT1 Model for Uranium-Induced Nephrotoxicity Pathway Study.

Journal of toxicology·2026

Same author

New CT-based dural ectasia criteria using machine learning to diagnose Marfan and Loeys-Dietz syndromes.

European heart journal. Imaging methods and practice·2026

Same author

Assessing the adequacy of funding for robotic-surgery hospital stays: a focused cost analysis based on 1,722 procedures in a French university hospital.

Journal of robotic surgery·2026

Same author

Incidence and Progression of Chronic Kidney Disease after Vascularized Composite Allotransplantation.

Plastic and reconstructive surgery·2026

Same author

Accuracy of Dexcom G6® and FreeStyle Libre® Sensors in Standardized Hypoxia Conditions: A Randomized Controlled Trial-FOX Study.

Diabetes technology & therapeutics·2026

Search research articles

Related Experiment Video

Updated: Jul 4, 2025

Orthotopic Hind Limb Transplantation in the Mouse

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

[Organ conservation and transportation modalities].

Marine Coué¹, Thierry Hauet², Lionel Badet³

¹Unité Ischémie reperfusion, métabolisme et inflammation stérile en transplantation (IRMETIST), UMR U1313, CHRU de Poitiers, Poitiers, France.

La Revue Du Praticien

|January 31, 2024

Summary

Organ preservation techniques are evolving to meet the challenges of donor age and comorbidities. New solutions and perfusion technologies, including normothermic machine perfusion, are improving graft viability for transplantation.

Keywords:

Organ Transplantation

More Related Videos

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

Published on: September 28, 2022

Related Experiment Videos

Last Updated: Jul 4, 2025

Orthotopic Hind Limb Transplantation in the Mouse

Orthotopic Hind Limb Transplantation in the Mouse

Published on: February 12, 2016

Study of Experimental Organ Donation Models for Lung Transplantation

Study of Experimental Organ Donation Models for Lung Transplantation

Published on: March 15, 2024

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

A Modified Murine Heterotopic Heart Transplant Protocol Matching Contemporary Standards of Aseptic Technique, Anesthesia, and Analgesia

Published on: September 28, 2022

Area of Science:

Transplantation immunology
Organ preservation science
Surgical innovation

Context:

Organ preservation is critical for successful transplantation.
Donor demographics (age, comorbidities) necessitate advanced preservation methods.
Current preservation techniques face limitations with evolving donor criteria.

Purpose:

To review the evolution of organ preservation and transportation modalities.
To highlight advancements in preservation solutions and perfusion technologies.
To discuss emerging concepts in organ care.

Summary:

Preservation solutions have evolved towards extracellular compositions with new molecules like high molecular weight polyethylene glycols.
Perfusion technologies have advanced, including normothermic abdominal circulation and machine perfusion systems utilizing hypothermia or normothermia with oxygenation.
New molecules and integrated perfusion, evaluation, and rehabilitation units represent the latest developments.

Impact:

Improved organ graft quality and viability.
Enhanced outcomes in organ transplantation.
Potential for expanded donor pool and reduced organ discard rates.