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A systematic approach to microbial forensics.

T J J Inglis1,2,3

  • 1Pathology and Laboratory Medicine, School of Medicine, University of Western Australia, Crawley, WA 6009, Australia.

Journal of Medical Microbiology
|February 2, 2024
PubMed
Summary
This summary is machine-generated.

The COVID-19 pandemic spurred biotech advances, enhancing microbial forensics. Integrating new and existing methods improves evidence gathering for infection science investigations.

Keywords:
Bacillus anthracisSARS-COV-2bioforensicsbiopreparednessbiosecuritybiosurveillancebioweapon investigationemerging infectious diseaseinfection scienceintegrated systems biologymicrobial forensics

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Area of Science:

  • Infection Science
  • Forensic Science
  • Biotechnology

Background:

  • The COVID-19 pandemic accelerated biotechnological advancements relevant to infection science.
  • Existing microbial forensic toolkits require updating to leverage these new technologies.
  • Effective microbial forensics is crucial for establishing causality and responsibility in investigations.

Purpose of the Study:

  • To explore the integration of novel analytical techniques with established forensic methods for microbial forensics.
  • To enhance the speed and effectiveness of evidence acquisition in infection-related investigations.
  • To outline a systematic approach for framing and shaping microbiological evidence into a clear investigative narrative.

Main Methods:

  • Review and synthesis of recent developments in biotechnology and infection science.
  • Conceptual integration of novel analytical techniques with traditional forensic methodologies.
  • Emphasis on a systematic approach to hypothesis generation, testing, and refinement in forensic investigations.

Main Results:

  • Novel analytical techniques can significantly speed up evidence acquisition in microbial forensics.
  • Integration of diverse methods strengthens the ability to demonstrate causal relationships and attribute responsibility.
  • A systematic approach ensures evidence is framed effectively within the broader investigative context.

Conclusions:

  • Modernizing the microbial forensic toolkit with advanced biotechnologies is essential.
  • A multidisciplinary, systematic approach enhances the efficiency and impact of microbial forensic investigations.
  • Developing integrated training exercises is key to practical implementation of these enhanced methods.