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Incurred sample reanalysis (ISR) in clinical bioanalysis-Is it really a one-size-fits-all solution?

Nuggehally R Srinivas1, Michael G Bartlett2

  • 1Department of Clinical Pharmacology and Pharmacometrics, Longboard Pharmaceuticals, La Jolla, CA, USA.

Biomedical Chromatography : BMC
|February 5, 2024
PubMed
Abstract

No abstract available in PubMed .

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A sample refers to a smaller subset representative of a larger population. In analytical chemistry, studying or analyzing an entire population is often impractical or impossible. Therefore, samples are used to draw inferences and generalize the whole population. The sampling method selects individuals or items from a population to create a sample. Standard sampling methods include random, judgemental, systematic, stratified, and cluster sampling. 
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Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
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