Related Experiment Video
Updated: Jul 4, 2025
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
DETERMINANTS OF PRETERM BIRTH AMONG MOTHERS WHO GAVE BIRTH AT A REFERRAL HOSPITAL, NORTHWEST ETHIOPIA: UNMATCHED
S Feleke1, A Mengsit2, A Kassa3
11Department of Public Health, Collage of Health Sciences, Woldia University, Ethiopia.
Insights
Preterm birth risk factors in Ethiopia include antepartum hemorrhage, premature rupture of membranes, and pregnancy-induced hypertension. Conversely, primigravida and primiparous mothers showed a reduced likelihood of preterm birth.
Area of Science:
- Obstetrics and Gynecology
- Public Health
- Perinatology
Background:
- Preterm birth affects 15 million newborns annually, with over a million deaths globally.
- Preterm birth is significantly underreported and underestimated in developing nations, including Ethiopia.
- Identifying preterm birth determinants is crucial for targeted interventions and improved maternal and neonatal outcomes.
Purpose of the Study:
- To determine the factors associated with preterm birth among mothers delivering at Felege Hiwot Comprehensive Specialized Referral Hospital in Northwest Ethiopia.
Main Methods:
- An unmatched case-control study was conducted with 558 participants (140 cases, 418 controls).
- Participants were selected using simple random sampling.
- Data were analyzed using STATA version 14.
Main Results:
- Antepartum hemorrhage (AOR 3.53), premature rupture of membranes (AOR 8.9), pregnancy-induced hypertension (AOR 3.65), and multiple pregnancies (AOR 2.49) were significantly associated with increased preterm birth risk.
- Primigravida (AOR 0.16) and primiparity (AOR 0.054) were associated with a decreased likelihood of preterm birth.
Conclusions:
- Antepartum hemorrhage, premature rupture of membranes, pregnancy-induced hypertension, and multiple pregnancies are key risk factors for preterm birth in this Ethiopian population.
- First-time mothers (primigravida and primiparous) appear to have a protective effect against preterm birth.
- These findings highlight the need for focused antenatal care and risk management strategies for preterm birth in Northwest Ethiopia.
Abstract:
Preterm birth is described as babies that are born alive before the end of 37 weeks of pregnancy. About 15 million babies are born preterm annually and more than a million died due to complications. In developing nations, like Ethiopia, PTB is underreported and underestimated. Objective - to identify determinates of preterm birth among mothers who gave birth at Felege Hiwot Comprehensive Specialized Referral Hospital, Northwest Ethiopia. Unmatched case-control study design was conducted. The total sample size was 558 mothers 140 cases and 418 controls. Simple random sampling was used to select the study population. Data were coded and entered into Epidata, version 3.2, and was analyzed by using STATA version 14. Mothers with a history of antepartum hemorrhage (AOR 3.53, 95% CI 1.31-9.47), premature rupture of membrane (AOR 8.9, 95% CI 4.51-17.57), pregnancy-induced hypertension (AOR 3.65, 95% CI 1.78-7.51), history of multiple pregnancies (AOR 2.49, 95% CI 0.89-6.95), primigravida (AOR 0.16, 95% CI 0.03-0.97) and Primiparity(AOR 0.054, 95% CI 0.05-0.64) had statistically significant association with experiencing preterm birth. The odds of giving preterm birth were higher among women with antepartum hemorrhage, PIH, PROM, and multiple pregnancies, but lower among primigravida and primiparous mothers.
Related Concept Videos
01:07Teratogenicity
02:27Background and Environment Affect Phenotype
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...