Correlation of Ocular Biometry with Axial Length in Elderly Japanese

Ocular parameters are not only useful for diagnosing diseases but also for guiding treatment approaches. A lot of previous studies have reported ocular parameters and its relations before cataract surgery. However, despite ethnic differences in ocular biometry, few reports have dealt with Japanese. Hence, this retrospective cross-sectional study aimed to measure parameters of preoperative cataract patients and examines the correlations between each parameter in Japanese elderly people.

The 210 subjects had their ocular axial lengths measured with OA-2000. The endpoints were ocular axial length (AL), central corneal thickness (CCT), average anterior corneal radius of curvature (CR), white-to-white (WTW), anterior chamber depth (ACD), and lens thickness (LT). Our analyses utilized the eye with the longer AL in each person. Each parameter was analyzed for correlations in a round-robin manner. Regression analyses were performed on parameters correlated with AL.

The parameters correlated with AL were CR (r = 0.33, P < 0.0001), WTW (r = 0.29, P < 0.0001), ACD (r = 0.59, P < 0.0001), and LT (r = -0.30, P < 0.0001). These parameters related to AL in all simple regression equations (CR (P < 0.0001), WTW (P = 0.0002), ACD (P < 0.0001), LT (P = 0.0001)). In multiple regression analyses, CR, ACD, and LT might relate to AL (CR (P = 0.0002), ACD (P < 0.0001), LT (P = 0.018)). LT tended to be thinner as AL increased, while CR, WTW, and ACD tended to increase.

This information may be useful in developing strategies for ophthalmic surgery, as it provides information on the location of intraocular tissues. Various parameters have been used in intraocular lens (IOL) power calculations in recent years and knowledge of the interrelationship among parameters may be useful in determining IOL power according to ethnicity in the future.