Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Detection of Gross Error: The Q Test01:00

Detection of Gross Error: The Q Test

6.1K
When one or more data points appear far from the rest of the data, there is a need to determine whether they are outliers and whether they should be eliminated from the data set to ensure an accurate representation of the measured value. In many cases, outliers arise from gross errors (or human errors) and do not accurately reflect the underlying phenomenon. In some cases, however, these apparent outliers reflect true phenomenological differences. In these cases, we can use statistical methods...
6.1K
Censoring Survival Data01:09

Censoring Survival Data

92
Survival analysis is a statistical method used to analyze time-to-event data, often employed in fields such as medicine, engineering, and social sciences. One of the key challenges in survival analysis is dealing with incomplete data, a phenomenon known as "censoring." Censoring occurs when the event of interest (such as death, relapse, or system failure) has not occurred for some individuals by the end of the study period or is otherwise unobservable, and it might have many different...
92
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

41
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
41
Statistical Analysis: Overview01:11

Statistical Analysis: Overview

6.6K
When we take repeated measurements on the same or replicated samples, we will observe inconsistencies in the magnitude. These inconsistencies are called errors. To categorize and characterize these results and their errors, the researcher can use statistical analysis to determine the quality of the measurements and/or suitability of the methods.
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...
6.6K
Truncation in Survival Analysis01:09

Truncation in Survival Analysis

208
Truncation in survival analysis refers to the exclusion of individuals or events from the dataset based on specific criteria related to the time of the event. This exclusion can happen in two primary forms: left truncation and right truncation.
Left truncation occurs when individuals who experienced the event of interest before a certain time are not included in the study. This is often due to a "delayed entry" into the study where only those who survive until a certain entry point are...
208
Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

1.6K
Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This...
1.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pattern-Mixture Models for Missing Data.

JAMA·2025
Same author

Multiple imputation of more than one environmental exposure with nondifferential measurement error.

Biostatistics (Oxford, England)·2023
Same author

ASSESSING SELECTION BIAS IN REGRESSION COEFFICIENTS ESTIMATED FROM NONPROBABILITY SAMPLES WITH APPLICATIONS TO GENETICS AND DEMOGRAPHIC SURVEYS.

The annals of applied statistics·2022
Same author

Estimands, Estimators, and Estimates.

JAMA·2021
Same author

University of Pennsylvania 11th annual conference on statistical issues in clinical trials: Estimands, missing data and sensitivity analysis (afternoon panel session).

Clinical trials (London, England)·2019
Same author

Correlation of Peripheral Immunity With Rapid Amyotrophic Lateral Sclerosis Progression.

JAMA neurology·2017
Same journal

Mental Health in College Students: From Epidemiological Findings to Sustainable Policies.

Annual review of clinical psychology·2026
Same journal

Sex Differences in Affective Disorders: A Developmental Neuroscience Framework on the Role of Puberty.

Annual review of clinical psychology·2026
Same journal

Interpersonal Psychotherapy for the Treatment of Depression Among Adults and Adolescents.

Annual review of clinical psychology·2026
Same journal

Body-Focused Repetitive Behavior Disorders: From Competing Paradigms Toward Iterative Integration.

Annual review of clinical psychology·2026
Same journal

Assessment and Treatment of Bipolar Disorder in the Community.

Annual review of clinical psychology·2026
Same journal

Objective Assessment in Clinical Psychological Science: Progress in Wearable Alcohol Biosensors.

Annual review of clinical psychology·2026
See all related articles

Related Experiment Video

Updated: Jul 3, 2025

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
07:10

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain

Published on: March 13, 2020

9.7K

Missing Data Analysis.

Roderick J Little1

  • 1Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA;

Annual Review of Clinical Psychology
|February 12, 2024
PubMed
Summary
This summary is machine-generated.

This review covers methods for handling missing data in clinical psychology, detailing techniques like imputation and maximum likelihood. Understanding missingness mechanisms is crucial for robust statistical analysis in psychological research.

Keywords:
ignorable missing dataincomplete datainformative missingnesslikelihood inferencemissing at randommissingness mechanismpartially missing at random

More Related Videos

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K

Related Experiment Videos

Last Updated: Jul 3, 2025

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain
07:10

Untargeted Liquid Chromatography-Mass Spectrometry-Based Metabolomics Analysis of Wheat Grain

Published on: March 13, 2020

9.7K
Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

14.5K
Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
08:03

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

2.2K

Area of Science:

  • Psychology
  • Statistics
  • Clinical Research

Background:

  • Missing data is a common challenge in clinical psychology studies.
  • Incomplete datasets can bias results and reduce statistical power.
  • Effective handling of missing data is essential for valid research conclusions.

Purpose of the Study:

  • To provide a comprehensive review of methods for addressing missing data in clinical psychology.
  • To define missing data and present a taxonomy of analytical approaches.
  • To discuss the impact of missingness mechanisms on analytical method performance.

Main Methods:

  • Review of existing literature on missing data handling techniques.
  • Categorization of methods including complete-case analysis, weighting, maximum likelihood, Bayesian methods, and imputation (single and multiple).
  • Discussion of augmented inverse probability weighting and robust inference strategies.

Main Results:

  • A taxonomy of missing data analysis methods is presented.
  • The critical role of missingness mechanisms (e.g., missing at random) in method selection is highlighted.
  • Strategies for robust inference and handling missing not at random data are discussed.

Conclusions:

  • Selection of appropriate missing data handling methods depends on the nature of missingness.
  • Understanding missing data mechanisms is fundamental for accurate and reliable clinical psychology research.
  • Further research into robust inference methods is warranted for complex missing data scenarios.