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Updated: Jul 3, 2025

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
Renal cell carcinoma metastasis without a primary: A case report
Basil Razi1, Dane Cole-Clark1, Duncan Self1
1Department of Urology, Gosford Hospital, Gosford, NSW, Australia.
Abstract:
In Australia, approximately 3 % of all cancers diagnosed each year are renal cancers. Renal Cell Carcinoma (RCC) represents 90 % of all primary renal malignancies. RCC are slow growing and often asymptomatic, thus are often found incidentally. Here we present the case of a 76-year-old male who was found to have a metastatic RCC in a para-aortic lymph node with no primary lesion. He underwent a retroperitoneal lymphadenectomy and 15 months after the surgery, has had no signs of primary tumours or metastasis. This case reports on a rare instance of metastatic RCC without an identified primary renal malignancy.

