The effect of training procedures on fixed-interval responding following septal lesions in rats

Two experiments were conducted to assess the effects of training procedures on fixed-interval (FI) performance of rats with septal lesions. In Experiment 1, rats with septal lesions that had extensive preoperative FI experience responded at higher rates than did control rats in early periods of the FI and at lower rates during the later period of the FI for the first 10 sessions after surgery. Their subsequent FI behavior became equivalent to that of control rats. In Experiment 2, septal rats that were trained on an FI schedule of reinforcement entirely after surgery by gradually increasing the FI requirements had FI performance equivalent to that of rats with control operations. The results suggest that septal lesions result in a transient disruption in the FI performance of rats with previous FI experience without affecting the acquisition of appropriate FI behavior.