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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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Sellar Reconstruction With a Bioabsorbable Plate After Endoscopic Transsphenoidal Pituitary Adenoma Resection: Safe
Ryan Kendall Thorpe1, Mark C Dougherty2, Jarrett E Walsh1
1Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City, IA, USA.
The Annals of Otology, Rhinology, and Laryngology
|February 19, 2024
Summary
Resorb-X plate (RXP) sellar reconstruction after endoscopic endonasal transsphenoidal surgery (EETS) for pituitary adenoma is safe and effective. This method shows low rates of cerebrospinal fluid leak and meningitis, potentially replacing autologous grafts.
Area of Science:
- Neurosurgery
- Endocrinology
- Medical Devices
Background:
- Endoscopic endonasal transsphenoidal surgery (EETS) is a common approach for pituitary adenoma resection.
- Sellar reconstruction is crucial after tumor removal to prevent complications.
- Various methods exist for sellar reconstruction, including autologous grafts and synthetic materials.
Purpose of the Study:
- To evaluate the outcomes of sellar reconstruction using the Resorb-X plate (RXP) after EETS for pituitary adenoma.
- To compare the safety and efficacy of RXP reconstruction with other reconstructive techniques.
Main Methods:
- Retrospective review of 620 EETS operations from 2005-2020.
- Identified 215 EETS operations (208 patients) between 2012-2020 who underwent RXP reconstruction for pituitary adenoma.
- Analyzed postoperative complications such as cerebrospinal fluid (CSF) leak and meningitis.
Main Results:
- Mean preoperative tumor volume was 6.8 cm³.
- Postoperative CSF leak occurred in 0.93% of patients (2/215).
- Postoperative meningitis occurred in 0.47% of patients (1/215).
- No cases of RXP extrusion were reported.
Conclusions:
- RXP sellar reconstruction after EETS for pituitary adenoma is associated with low rates of CSF leak and meningitis.
- These complication rates compare favorably to those reported for autologous grafts and flaps.
- RXP is a safe and effective option for sellar reconstruction, potentially eliminating the need for autologous tissue.
