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Ozone and Laser Effects on Dentin Hypersensitivity Treatment: A Randomized Clinical Study
Maurizio D'Amario1, Mariachiara Di Carlo1, Ali Jahjah1
1Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy.
Journal of Endodontics
|February 21, 2024
Summary
Ozone gas and diode laser treatments effectively reduce dentin hypersensitivity (DHS). Ozone therapy demonstrated superior long-term efficacy over diode lasers after six months.
Area of Science:
- Dental Science
- Biomedical Engineering
Background:
- Dentin hypersensitivity (DHS) affects a significant patient population.
- Current treatments for DHS vary in efficacy and duration.
Purpose of the Study:
- To compare the clinical effectiveness of diode laser therapy versus ozone gas application for treating dentin hypersensitivity.
- To evaluate the long-term outcomes of these interventions.
Main Methods:
- A randomized split-mouth study involved 44 patients with moderate DHS.
- Treatments included diode laser irradiation, ozone gas application, and a placebo.
- Dentin sensitivity was assessed using cold air and tactile stimuli at multiple time points.
Main Results:
- Both diode laser and ozone gas significantly reduced dentin hypersensitivity.
- Ozone gas treatment resulted in statistically lower sensitivity values compared to diode laser at the 6-month follow-up.
Conclusions:
- Diode laser and ozone gas are both viable treatments for dentin hypersensitivity.
- Ozone gas offers sustained effectiveness for dentin hypersensitivity treatment up to six months.

