Ultra-Sensitive and Stable Multiplexed Biosensors Array in Fully Printed and Integrated Platforms for Reliable...

Area of Science:

• Wearable biosensors
• Electrochemical sensing
• Perspiration analysis

Background:

• Electrochemical biosensors enable non-invasive physiological monitoring through sweat analysis.
• Integrating multiplexed sensors reliably on flexible platforms for long-term use remains challenging.

Purpose of the Study:

• To develop a fully inkjet-printed, integrated multiplexed biosensing patch.
• To achieve high stability, sensitivity, and reproducibility for wearable biosensing applications.

Main Methods:

• Utilized optimized ink formulations and droplet-assisted printing for precise control.
• Developed a unique interpenetrating interface design for enhanced sensor integration.
• Fabricated a multiplexed biosensing patch on a flexible platform.

Main Results:

• Achieved high sensitivities of 313.28 µA mm⁻¹ cm⁻² for glucose and 0.87 µA mm⁻¹ cm⁻² for alcohol.
• Demonstrated minimal sensor drift over 30 hours, indicating remarkable stability.
• Successfully integrated multiplexed sensors for reliable epidermal analysis.

Conclusions:

• The developed biosensing patch offers a stable and sensitive platform for non-invasive monitoring.
• This technology advances wearable devices for intelligent healthcare and diet monitoring.
• The inkjet printing approach enables controllable and reproducible fabrication of advanced biosensors.