Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

979
Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
979
Chemical Factors Affecting Respiration Centers01:31

Chemical Factors Affecting Respiration Centers

1.1K
Chemical factors such as changing CO2, O2, and H+ levels in arterial blood play a critical role in influencing respiration depth and rates. These variations are detected by chemoreceptors—specialized sensors located in two primary body areas. Central chemoreceptors are found throughout the brain stem, including the ventrolateral medulla, while peripheral chemoreceptors are located in the aortic arch and carotid arteries.
CO2 has a potent influence on respiration and is strictly regulated....
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sub-Second, Sensitive and Multispecies Detection of Volatile Organic Compounds Using a Mid-Infrared Broadband Supercontinuum Source and Upconversion Spectrometer.

Applied spectroscopy·2026
Same author

Multispecies gas detection using mid-infrared open-path Fourier transform and upconversion spectroscopy.

Optics express·2025
Same author

Optimizing data analysis for broadband mid-infrared absorption spectroscopy: A hybrid dataset approach.

Analytica chimica acta·2025
Same author

Broadening the diagnostic landscape of<i>Mycobacterium tuberculosis</i>infection: analyzing exhaled breath.

Journal of breath research·2025
Same author

Ultra-broadband coherent open-path spectroscopy for multi-gas monitoring in wastewater treatment.

Environmental science and ecotechnology·2025
Same author

Phosphorus-based heterojunction tunnel field-effect transistors: from atomic insights to circuit renovations.

Physical chemistry chemical physics : PCCP·2024

Related Experiment Video

Updated: Jul 2, 2025

Fast and Accurate Exhaled Breath Ammonia Measurement
06:27

Fast and Accurate Exhaled Breath Ammonia Measurement

Published on: June 11, 2014

13.5K

Real-Time Measurement of CH4 in Human Breath Using a Compact CH4/CO2 Sensor.

Yueyu Lin1, Dexter Manalili1, Amir Khodabakhsh1

  • 1Life Science Trace Detection Laboratory, Department of Analytical Chemistry and Chemometrics, Institute for Molecules and Materials, Radboud University, 6525 AJ Nijmegen, The Netherlands.

Sensors (Basel, Switzerland)
|February 24, 2024
PubMed
Summary

A new, portable breath sensor accurately measures methane (CH4) and carbon dioxide (CO2) in real-time. This non-invasive tool can help monitor health conditions by analyzing exhaled breath composition.

Keywords:
breathcarbon dioxidecorrection functionsmethanereal-time measurements

More Related Videos

The Use of an Automated System GreenFeed to Monitor Enteric Methane and Carbon Dioxide Emissions from Ruminant Animals
11:02

The Use of an Automated System GreenFeed to Monitor Enteric Methane and Carbon Dioxide Emissions from Ruminant Animals

Published on: September 7, 2015

22.0K
Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
08:23

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

Published on: March 9, 2018

8.9K

Related Experiment Videos

Last Updated: Jul 2, 2025

Fast and Accurate Exhaled Breath Ammonia Measurement
06:27

Fast and Accurate Exhaled Breath Ammonia Measurement

Published on: June 11, 2014

13.5K
The Use of an Automated System GreenFeed to Monitor Enteric Methane and Carbon Dioxide Emissions from Ruminant Animals
11:02

The Use of an Automated System GreenFeed to Monitor Enteric Methane and Carbon Dioxide Emissions from Ruminant Animals

Published on: September 7, 2015

22.0K
Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry
08:23

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

Published on: March 9, 2018

8.9K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Medical Diagnostics

Background:

  • Elevated methane (CH4) in exhaled breath indicates certain health conditions.
  • Non-invasive monitoring requires compact, affordable, and transportable sensors.
  • Simultaneous measurement of CH4 and carbon dioxide (CO2) aids in determining end-tidal concentrations.

Purpose of the Study:

  • To develop and validate a compact, inexpensive, and transportable sensor for real-time measurement of exhaled methane (CH4) and carbon dioxide (CO2).
  • To address and correct for water vapor interference in CH4/CO2 measurements.
  • To enable accurate, non-invasive health monitoring through breath analysis.

Main Methods:

  • Utilized a commercial tunable diode laser absorption spectroscopy (TDLAS) module for CH4 and CO2 detection.
  • Developed and implemented experimental correction functions for water vapor interference.
  • Integrated a custom-built breath sampler for real-time exhalation analysis.

Main Results:

  • The developed sensor accurately measured real-time CH4 and CO2 profiles in exhaled breath.
  • Correction functions effectively mitigated water vapor interference.
  • Achieved minimum detection limits of approximately 80 ppbv for CH4 and 700 ppmv for CO2 within a 1.5-second measurement time.

Conclusions:

  • The TDLAS-based breath sensor is capable of accurate, real-time, non-invasive monitoring of exhaled CH4 and CO2.
  • The sensor's portability and cost-effectiveness make it suitable for widespread health diagnostics.
  • This technology offers a promising avenue for early detection and management of various health conditions.