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Effect Of Intravitreal Perfluoro Propane (C3f8) In The Management Of Symptomatic Vitreomacular Traction.

Syeda Minahil Gardezi¹, Khujasta Gul¹, Misbah Batool¹

¹MMDC-Multan & Bodla Eye Care, Multan, Pakistan.

Journal of Ayub Medical College, Abbottabad : JAMC

|February 26, 2024

Summary

A single C3F8 injection effectively treated symptomatic vitreomacular traction (VMT) in six out of nine patients. This study suggests C3F8 is a safe and cost-effective alternative for VMT treatment.

Keywords:

Hexafluoropropylene (C3F8); Sulphur hexafluoride (SF6); Vitreomacular traction; Vitrectomy

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Area of Science:

Ophthalmology
Retinal Diseases
Surgical Innovation

Background:

Symptomatic vitreomacular traction (VMT) requires effective treatment options.
Current treatments like pars plana vitrectomy and Ocriplasmin have limitations.

Purpose of the Study:

To evaluate the efficacy of a single 0.3ml intravitreal C3F8 injection for treating symptomatic VMT.

Main Methods:

Retrospective interventional study involving nine patients with symptomatic VMT.
Patients received a single 0.3ml C3F8 injection.
Follow-up included clinical assessment and optical coherence tomography (OCT) scans at one and four weeks post-injection.

Main Results:

Complete resolution of VMT was observed in 4 patients after one week.
An additional 2 patients showed VMT release by four weeks.
Overall, 6 out of 9 patients (66.7%) achieved complete resolution of VMT.

Conclusions:

Intravitreal C3F8 injection is a viable treatment for symptomatic VMT.
C3F8 offers a potentially safer and more cost-effective alternative compared to pars plana vitrectomy or Ocriplasmin.