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Low-cost seizure simulation in low-technology mannequins for resource-constrained settings: An innovative approach to

Naveen Paliwal1, Pooja Bihani1, Dinker R Pai2

  • 1Department of Anaesthesiology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India.

Indian Journal of Anaesthesia
|February 26, 2024
PubMed
Abstract

No abstract available in PubMed .

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Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's proficiency in drug...