Cardiovascular disease and lung cancer
Mikhail de Jesus1, Anindita Chanda2, Titas Grabauskas3
1Department of Cardiology, University of Connecticut Hartford Hospital, Hartford, CT, United States.
Frontiers in Oncology
|February 27, 2024
Summary
Lung cancer patients often face cardiovascular disease (CVD) due to shared risk factors and cancer treatments. Managing these complex cases requires a team approach to prevent and treat heart issues.
Area of Science:
- Oncology and Cardiology
- Cancer Therapeutics and Cardiovascular Complications
Background:
- Lung cancer is a leading global cause of death.
- Cardiovascular disease (CVD) is a significant cause of illness and death in lung cancer patients.
- Shared risk factors like smoking and obesity link lung cancer and CVD.
Purpose of the Study:
- To review shared risk factors between lung cancer and CVD.
- To outline cardiovascular toxicities of lung cancer treatments.
- To guide prevention and management of CVD in lung cancer patients.
Main Methods:
- Literature review of shared risk factors.
- Analysis of cardiotoxicities from lung cancer therapies.
- Synthesis of evidence for CVD prevention and management strategies.
Main Results:
- Identified common risk factors including smoking, hypertension, and diabetes.
- Detailed the spectrum of cardiovascular toxicities associated with lung cancer therapeutics.
- Provided strategies for managing short- and long-term CVD in non-small cell (NSCLC) and small cell (SCLC) lung cancer.
Conclusions:
- Effective management necessitates understanding treatment-related cardiovascular risks.
- Multidisciplinary care involving oncologists, cardiologists, and primary care physicians is crucial.
- Proactive prevention and management of CVD improve outcomes for lung cancer patients.
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