Related Experiment Video
Updated: Jul 30, 2026

06:14
Induction of Periodontitis via a Combination of Ligature and Lipopolysaccharide Injection in a Rat Model
Published on: February 17, 2023
3.9K
Dental Implants in 18 Patients with Systemic Scleroderma: A Retrospective Radiographic Analysis Over a 5-Year Period
The International Journal of Oral & Maxillofacial Implants
|February 28, 2024
Summary
Dental implant bone loss in patients with systemic scleroderma (SSc) was radiologically assessed. Results show comparable marginal bone loss to healthy individuals, suggesting SSc does not significantly increase implant complications.
Area of Science:
- Oral and Maxillofacial Surgery
- Periodontology
- Radiology
Background:
- Systemic scleroderma (SSc) is associated with premature tooth loss.
- Dental implants are a common solution for tooth loss.
- Radiological assessment of bone loss around implants in SSc patients is crucial.
Purpose of the Study:
- To radiologically investigate bone loss at dental implants in patients with systemic scleroderma (SSc).
- To compare peri-implant bone loss in SSc patients with existing literature data from healthy individuals.
Main Methods:
- Analysis of mesial and distal bone level changes on panoramic and intraoral radiographs of 61 implants in 18 SSc patients.
- Double-checking by three independent raters and interrater reliability testing using Cohen's kappa.
- Estimation of mean bone loss using linear regression analysis over a maximum observation period of 60 months.
Main Results:
- Mean peri-implant bone loss in the right posterior mandible was 1.68 mm distally and 1.65 mm mesially.
- Mean peri-implant bone loss in the left posterior maxilla was 0.61 mm distally and 0.59 mm mesially.
- Overall mean bone loss at 60 months post-surgery was 1.05 mm.
Conclusions:
- Marginal bone loss around dental implants in SSc patients is comparable to that observed in healthy subjects.
- Systemic scleroderma does not appear to significantly increase the risk of peri-implant bone loss.
- Radiological monitoring of dental implants in SSc patients can follow standard protocols.

