Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

4.5K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

User-Friendly Summary of BI-RADS v2025: What Practicing Radiologists Want to Know.

AJR. American journal of roentgenology·2026
Same author

The Lifecycle and Role of Faculty-Trainee Relationships in Physician Development and Wellness: A Framework Grounded in the AAMC Faculty-Resident Compact.

Academic radiology·2026
Same author

Leading with C.A.R.E: A Framework to Foster Belonging and Well-Being in Radiology.

Academic radiology·2025
Same author

Interplay of BMI and volumetric breast density measures and breast cancer risk for black and white women.

Breast cancer research : BCR·2025
Same author

Dynamic AI-assisted ipsilateral tissue matching for digital breast tomosynthesis.

European journal of radiology·2025
Same author

Racial Differences in Screening Eligibility by Breast Density After State-Level Insurance Expansion.

JAMA network open·2025

Related Experiment Video

Updated: Jul 1, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

22.5K

Digital Breast Tomosynthesis: What Have We Learned?

Reni Butler1, Emily F Conant2, Liane Philpotts1

  • 1Yale University School of Medicine, Department of Radiology and Biomedical Imaging, New Haven, CT.

Journal of Breast Imaging
|March 1, 2024
PubMed
Summary

Digital breast tomosynthesis (DBT) offers superior breast imaging over 2D mammography, improving cancer detection and reducing recall rates. DBT also enhances diagnostic accuracy and simplifies work-up, with advancements addressing radiation concerns.

Keywords:
breastscreeningtomosynthesis

More Related Videos

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model
08:32

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Published on: October 2, 2020

6.3K
Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
13:44

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

Published on: August 30, 2013

42.9K

Related Experiment Videos

Last Updated: Jul 1, 2025

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging
15:48

Tracking the Mammary Architectural Features and Detecting Breast Cancer with Magnetic Resonance Diffusion Tensor Imaging

Published on: December 15, 2014

22.5K
Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model
08:32

Using Computer-based Image Analysis to Improve Quantification of Lung Metastasis in the 4T1 Breast Cancer Model

Published on: October 2, 2020

6.3K
Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns
13:44

Detection of Architectural Distortion in Prior Mammograms via Analysis of Oriented Patterns

Published on: August 30, 2013

42.9K

Area of Science:

  • Radiology and Medical Imaging
  • Oncology
  • Breast Health

Background:

  • Digital breast tomosynthesis (DBT) is emerging as a more effective breast imaging technology than traditional 2D digital mammography (DM).
  • DBT demonstrates higher sensitivity and specificity in screening, leading to increased cancer detection and decreased recall rates.
  • In diagnostic settings, DBT improves accuracy and streamlines patient work-up.

Purpose of the Study:

  • To evaluate the clinical benefits and advancements in Digital Breast Tomosynthesis (DBT) compared to 2D Digital Mammography (DM).
  • To assess the impact of DBT on cancer detection rates, diagnostic accuracy, and radiation exposure.
  • To review the characteristics of cancers detected by DBT and the role of DBT in guiding biopsies.

Main Methods:

  • Review of accumulating data and meta-analyses on DBT performance in screening and diagnostic settings.
  • Evaluation of synthesized 2D mammography (SM) in mitigating radiation concerns associated with DBT.
  • Analysis of cancer characteristics (histology, molecular type, nodal status) detected by DBT.
  • Assessment of DBT's role in detecting subtle findings like architectural distortion and guiding biopsies.

Main Results:

  • DBT significantly increases cancer detection rates and reduces abnormal interpretation (recall) rates compared to DM alone.
  • Synthesized 2D mammography (SM) has largely alleviated concerns regarding increased radiation exposure from DBT.
  • DBT detects smaller invasive cancers, often with Grade 1 histology and Luminal A molecular characteristics, and may identify higher-grade cancers as node-negative.
  • DBT improves the detection of subtle architectural distortions, including spiculated invasive carcinomas and benign entities like radial scars.
  • DBT-guided biopsy procedures show potential for improved efficiency and reduced radiation during percutaneous breast biopsy.

Conclusions:

  • Digital breast tomosynthesis (DBT) represents a significant advancement in breast imaging, offering superior cancer detection and diagnostic accuracy.
  • Ongoing research focuses on refining synthesized 2D mammography (SM) and improving DBT artifact reduction.
  • DBT enhances the detection of early-stage cancers and aids in the diagnostic evaluation of subtle findings, with DBT-guided biopsies showing promise for procedural efficiency.