Related Experiment Video
Updated: Jul 1, 2025

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Prevention of Prosthetic Joint Infection Prior to Incision
Abstract:
Prosthetic joint infection (PJI) remains a major cause of failure in total joint arthroplasty. This complication begets an increase in morbidity and mortality along with significant costs to the healthcare system. The use of prophylactic antibiotics has significant decreased the incidence of this complication. However, the incidence of PJI has not drastically decreased over the last 50 years. This review explores the history, current concepts, and future developments for prevention of PJI prior to incision in total joint arthroplasty.
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