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Related Concept Videos

Spinal Cord01:26

Spinal Cord

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The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
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Spinal Nerves: Anatomy01:23

Spinal Nerves: Anatomy

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Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
There are 31 bilateral pairs of spinal nerves, each emerging from the spinal cord through the intervertebral foramina—openings between adjacent vertebrae. These nerves are...
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Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
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The Spinal Cord01:54

The Spinal Cord

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The spinal cord is the body’s major nerve tract of the central nervous system, communicating afferent sensory information from the periphery to the brain and efferent motor information from the brain to the body. The human spinal cord extends from the hole at the base of the skull, or foramen magnum, to the level of the first or second lumbar vertebra.
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Spinal Cord: Cross-sectional Anatomy01:16

Spinal Cord: Cross-sectional Anatomy

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The cross-sectional anatomy of the spinal cord offers a detailed view of its complex structure and function within the central nervous system. At the core of the spinal cord lies the gray matter, characterized by its butterfly or "H"-shaped appearance in cross-section. This central region is enveloped by white matter, with the overall structure divided into symmetrical halves by the dorsal median sulcus and the ventral median fissure.
Gray Matter and its Components
Central to the gray matter is...
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Spinal Cord: Gross Anatomy01:15

Spinal Cord: Gross Anatomy

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The spinal cord resides within the protective confines of the vertebral column. It is the main pathway for information traveling between the brain and the body. It plays a fundamental role in nearly all bodily functions, from simple reflexes to complex motor movements. The spinal cord begins at the medulla oblongata at the base of the brainstem and extends downward, terminating at the conus medullaris near the first and second lumbar vertebrae. The spinal cord's length in adults is...
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Infected charcot spine.

Hiromu Yoshizato1, Tadatsugu Morimoto1, Toshihiro Nonaka1

  • 1Department of Orthopaedic Surgery, Faculty of Medicine Saga University Saga Japan.

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PubMed
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Infected charcot spine (ICS) can cause severe vertebral destruction with minimal back pain, complicating diagnosis. Worsening chronic charcot spine symptoms warrant investigation for infection.

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Area of Science:

  • Spine surgery
  • Infectious diseases
  • Orthopedic surgery

Background:

  • Charcot spine, a severe complication of spinal deformities, presents unique diagnostic challenges.
  • Infection can affect the spine, leading to significant bone destruction.

Observation:

  • Patients with infected charcot spine (ICS) may exhibit minimal or absent back pain, despite extensive vertebral damage.
  • This paradoxical presentation can delay diagnosis and treatment.

Findings:

  • Understanding the pathophysiology of ICS is critical for differentiating it from other spinal conditions.
  • The differential diagnosis of ICS requires careful consideration of infectious etiologies.

Implications:

  • Increased suspicion for infection is warranted with worsening symptoms in patients with chronic charcot spine.
  • Early and accurate diagnosis of ICS is essential to prevent further vertebral destruction and neurological compromise.