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Updated: Jul 1, 2025

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Multifocal Electroretinograms
Published on: December 4, 2011
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A Case of Hydroxychloroquine Toxicity as Evidenced by Visual Field Changes
Aliya Centner1, Donald J Centner2
1Medicine, University of Central Florida College of Medicine, Orlando, USA.
Cureus
|March 5, 2024
Summary
Hydroxychloroquine (Plaquenil) can cause rare retinal toxicity. Early detection through regular eye exams is crucial, even without obvious macular changes, to prevent vision loss in patients with autoimmune diseases.
Area of Science:
- Ophthalmology
- Rheumatology
- Pharmacology
Background:
- Hydroxychloroquine sulfate (Plaquenil®) is a disease-modifying anti-rheumatic drug (DMARD) used for autoimmune diseases.
- A rare but serious complication is hydroxychloroquine-induced retinal toxicity.
- Long-term use necessitates careful monitoring for ocular side effects.
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