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Updated: Jul 1, 2025
10:46
A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
10.7K
Association between sun exposure habits and disease progression in multiple sclerosis
Jing Wu1, Tomas Olsson2, Lars Alfredsson2,3,4
1Department of Neurobiology, Care Sciences and Society, Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
European Journal of Neurology
|March 5, 2024
Summary
Low sun exposure is linked to faster multiple sclerosis (MS) progression and poorer quality of life. Increasing sun exposure appears to reduce the risk of unfavorable outcomes in MS patients.
Area of Science:
- Neurology
- Epidemiology
- Environmental Health
Background:
- Higher latitudes correlate with increased multiple sclerosis (MS) incidence and severity.
- Sun exposure is a potential environmental factor influencing MS.
Purpose of the Study:
- To investigate the impact of sun exposure habits on MS disease progression.
- To assess the effect of sun exposure on health-related quality of life in MS patients.
Main Methods:
- A population-based case-control study followed 3314 MS patients for up to 15 years.
- Sun exposure habits at diagnosis were used for categorization.
- Disease progression was measured using the Expanded Disability Status Scale (EDSS) and disability worsening events.
Main Results:
- Low sun exposure was associated with faster EDSS progression and increased risk of disability worsening.
- Reduced sun exposure correlated with higher risks of reaching EDSS 3 and EDSS 4.
- A trend indicated that increased sun exposure was linked to a lower risk of adverse outcomes.
Conclusions:
- Very low sun exposure is associated with worse MS disease progression.
- Limited sun exposure negatively impacts the health-related quality of life in individuals with MS.
Keywords:
Expanded Disability Status Scaledisability worseningdisease activitylife qualitymultiple sclerosissun exposureMore Related Videos
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