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[Tea polyphenols improves depression-like behavior in aged type 2diabetes rats by regulating microglia polarization]

Haoran Xie1, Wenjuan Feng1, Xi Wang1

  • 1Department of Nutrition and Food Hygiene, School of Public Health, Shanxi Medical University, Key Laboratory of Coal Environmental Pathogenicity and Prevention, Taiyuan 030001, China.

Wei Sheng Yan Jiu = Journal of Hygiene Research
|March 5, 2024
PubMed
Summary

Tea polyphenols (TP) significantly improved depression-like behaviors in aged type 2 diabetes (T2DM) rats. This suggests TP may be a therapeutic agent by regulating neuroinflammation and boosting brain-derived neurotrophic factor (BDNF) levels.

Keywords:
aged type 2 diabetesbrain derived neurotrophic factordepression-like behaviormicroglia polarizationtea polyphenols

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