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Related Concept Videos

Fixing Double-strand Breaks02:04

Fixing Double-strand Breaks

The double-stranded structure of DNA has two major advantages. First, it serves as a safe repository of genetic information where one strand serves as the back-up in case the other strand is damaged. Second, the double-helical structure can be wrapped around proteins called histones to form nucleosomes, which can then be tightly wound to form chromosomes. This way, DNA chains up to 2 inches long can be contained within microscopic structures in a cell. A double-stranded break not only damages...
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The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
Anionic Chain-Growth Polymerization: Mechanism01:04

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Horizontal necklines correction with absorbable braided polydioxanone threads: Case series.

Kyu-Ho Yi1,2, Soo-Bin Kim1, Deborah Chua3

  • 1Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seodaemun-gu, Seoul, South Korea.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|March 6, 2024
PubMed
Summary
This summary is machine-generated.

Braided polydioxanone-barbed threads effectively reduce horizontal neck wrinkles. This novel treatment offers a secure and promising option for neck rejuvenation, showing significant aesthetic improvements.

Keywords:
horizontal necklineneck wrinklepolydioxanoneskin rejuvenationthread lifting

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Area of Science:

  • Dermatology
  • Aesthetic Medicine
  • Regenerative Medicine

Background:

  • Horizontal neck lines are a common cosmetic concern with limited treatment options.
  • Polydioxanone-barbed threads, with their braided structure, act as a scaffold for tissue regeneration.
  • No prior studies have explored polydioxanone-barbed threads for horizontal neck wrinkles.

Purpose of the Study:

  • To evaluate the efficacy and safety of using braided polydioxanone-barbed threads for treating horizontal neck wrinkles.
  • To assess the regenerative potential of these threads in the neck area.

Main Methods:

  • A retrospective case series of four female participants aged 41-46.
  • Treatment involved the concurrent application of polydioxanone-barbed threads for horizontal neck wrinkles.
  • An 8-week follow-up assessed wrinkle intensity using the Horizontal Neck Wrinkle Severity Scale and aesthetic improvement via the Global Aesthetic Improvement Scale (GAIS).

Main Results:

  • Significant reduction in horizontal neck wrinkle intensity observed at 8 weeks, maintaining statistical significance.
  • Excellent patient-reported GAIS scores (90%-100%) and physician-reported GAIS scores (100%).
  • No adverse effects, including the Tyndall effect, were reported.

Conclusions:

  • Subdermal polydioxanone-barbed threads are a safe and effective treatment for horizontal neck wrinkles.
  • This technique shows significant promise for skin rejuvenation in the horizontal neckline.
  • The braided structure facilitates a regenerative response, improving aesthetic outcomes.