Related Experiment Video
Updated: Jul 1, 2025

Remote Laboratory Management: Respiratory Virus Diagnostics
Published on: April 6, 2019
Rapid Review of Therapy Protocols for Public Health Emergencies
Bruce G Gordon1, Abigail E Lowe2, Christopher J Kratochvil3
1Assistant vice-chancellor for regulatory affairs, and executive chairman of the IRBs at the University of Nebraska Medical Center.
Abstract:
How research during a public health emergency is conducted is recognized as essential to the public health response to that emergency. Such research needs to undergo substantive and meaningful ethical review in a timely manner. Rapid ethical review may be accomplished through a number of mechanisms, including use of local rapid-response institutional review boards (IRBs). We describe use of such a model in the setting of the 2014 Ebola virus disease epidemic and the Rapid-Response IRB's subsequent transition to a multisite single IRB model during the current Covid-19 pandemic. The rapid-response review model is characterized by a small IRB with extensive use of alternate members with specific expertise and by close collaboration with the investigator in an iterative process.
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