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Updated: Jul 1, 2025

Left Coronary Artery Ligation: A Surgical Murine Model of Myocardial Infarction
Published on: August 9, 2022
Myocardial Infarction Presenting as Both Left Ventricular Aneurysm and Ventricular Septal Defect
Harshwardhan Khandait1, Sherif Elkattawy2, Jesus E Romero1
1Internal Medicine Department, RWJBarnabas Health/Trinitas Regional Medical Center, Elizabeth, USA.
This case report highlights a rare instance of acute myocardial infarction leading to both ventricular septal rupture and left ventricular aneurysm. Early diagnosis and intervention are crucial for managing these life-threatening mechanical complications.
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Case Reports
Background:
- Acute myocardial infarction (AMI) can precipitate rare but severe mechanical complications.
- Ventricular septal rupture (VSR) and left ventricular aneurysm (LVA) are infrequent but associated with high mortality.
- Reperfusion therapies have reduced the incidence of these complications.
Purpose of the Study:
- To report a rare case of concomitant apical LVA and VSR following AMI.
- To emphasize the importance of early diagnosis and management of mechanical complications post-myocardial infarction.
Main Methods:
- Case presentation of a 67-year-old male with acute myocardial infarction.
- Review of diagnostic modalities including echocardiography and left ventriculography.
- Discussion of treatment strategies for VSR and LVA.
Main Results:
- The patient presented with acute myocardial infarction complicated by both apical LVA and VSR.
- Diagnostic imaging confirmed the presence of these rare mechanical complications.
- Treatment decisions were guided by the identified complications and patient status.
Conclusions:
- VSR and LVA are rare, life-threatening mechanical complications of myocardial infarction.
- Prompt diagnosis using echocardiography and left ventriculography is essential.
- VSD necessitates urgent surgical repair; LVA management is case-specific.
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