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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Anetoderma after disseminated Mpox.

Andrés Grau-Echevarría1, Carolina Labrandero-Hoyos1, Rodrigo Peñuelas-Leal1

  • 1Dermatology Department, Consorcio Hospital General Universitario de Valencia, Valencia, Spain.

Journal of Cutaneous Pathology
|March 12, 2024
PubMed
Summary
This summary is machine-generated.

Mpox infection can lead to anetoderma, a rare skin condition characterized by loss of elastic fibers. This case highlights a unique instance of Mpox-induced anetoderma in an HIV-positive individual.

Keywords:
HIVanetodermamonkeypoxmpoxsyphilis

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Pathogenesis of Skin Conditions

Background:

  • Anetoderma is a rare skin disorder of unknown cause, linked to autoimmune conditions and infections.
  • Previous associations include Human Immunodeficiency Virus (HIV), syphilis, and poxviruses.
  • Mpox (formerly monkeypox) is a viral illness that can cause widespread skin lesions.

Observation:

  • A Human Immunodeficiency Virus (HIV)-positive patient presented with numerous Mpox lesions.
  • Following Mpox symptom resolution, the patient developed papular anetoderma.
  • The anetoderma lesions appeared in areas previously affected by Mpox.

Findings:

  • Biopsy confirmed significant loss of elastic fibers in the affected skin.
  • This confirmed a diagnosis of Mpox-induced anetoderma.
  • This represents a novel association between Mpox and anetoderma.

Implications:

  • This case suggests a potential link between Mpox infection and the development of anetoderma.
  • Further research is needed to understand the pathogenesis of Mpox-induced anetoderma.
  • This finding may have implications for managing skin complications in Mpox patients, particularly those with HIV.