Related Experiment Video
Updated: Jul 1, 2025

Quantification of Oculomotor Responses and Accommodation Through Instrumentation and Analysis Toolboxes
Published on: March 3, 2023
New forays into measurement of ocular biomechanics
Emma Hammelef1, Christopher J Rapuano2, Dominick A Benedetto3,4
1Sidney Kimmel Medical College at Thomas Jefferson University at Thomas Jefferson University.
Purpose Of Review:
The field of corneal biomechanics has rapidly progressed in recent years, reflecting technological advances and an increased understanding of the clinical significance of measuring these properties. This review will evaluate in-vivo biomechanical properties obtained by current technologies and compare them regarding their relevance to established biomechanical properties obtained by gold-standard ex-vivo techniques normally conducted on elastic materials.
Recent Findings:
Several new technologies have appeared in recent years, including vibrational optical coherence tomography (VOCT) and the corneal indentation device (CID). These techniques provide promising new opportunities for minimally invasive and accurate measurements of corneal viscoelastic properties.
Summary:
Alterations in corneal biomechanics are known to occur in several corneal degenerative diseases and after refractive surgical procedures. The measurement of corneal biomechanical properties has the capability to diagnose early disease and monitor corneal disease progression. Several new technologies have emerged in recent years, allowing for more accurate and less invasive measurements of corneal biomechanical properties, most notably the elastic modulus.

