Related Experiment Video
Updated: Jun 30, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Child Protection System Removal and Short-Interval Births Among Individuals With Prenatal Substance Use.
Julia Reddy1, Davida Schiff, Mishka Terplan
1Gillings School of Global Public Health, the Department of Obstetrics & Gynecology, and the School of Social Work, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; MassGeneral Hospital for Children, Harvard Medical School, Boston, Massachusetts; and Friends Research Institute, Baltimore, Maryland.
Early child protection system removal after substance-exposed births is linked to more, not fewer, subsequent substance-exposed births. This highlights the need for postpartum support services for mothers with substance use disorders.
Area of Science:
- Public Health
- Maternal Health
- Child Welfare
Background:
- Child protection systems often intervene post-birth for substance-exposed infants.
- These systems are not designed for postpartum parental support.
- Maternal substance use during pregnancy presents complex challenges.
Purpose of the Study:
- To examine the association between early child protection system involvement and subsequent high-risk birth trajectories.
- To investigate the impact of postpartum child removal on maternal substance use and birth outcomes.
- To inform interventions for parents with substance use during pregnancy.
Main Methods:
- Retrospective cohort study of mothers with substance-exposed births in California (2015).
- Analysis of 6,893 births with documented prenatal drug and alcohol exposure.
- Examined child protection system removal within 30 days postpartum and subsequent birth intervals and substance exposure.
Main Results:
- 20.4% of mothers experienced child protection system removal within 30 days of birth.
- Early removal was associated with increased risk of short-interval subsequent births (aHR 1.61).
- Early removal significantly increased risk of short-interval births with documented substance exposure (aHR 3.17).
- Child separation correlated with an increase in subsequent substance-exposed births.
Conclusions:
- Early child protection system removal following substance-exposed births is associated with adverse maternal and infant outcomes.
- Findings suggest child separation does not reduce, but may increase, subsequent substance-exposed births.
- There is a critical need for integrated public health and supportive services addressing parental substance use, treatment, and family well-being.
More Related Videos
Related Concept Videos
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Teratogenicity
Factors Affecting Drug Response: Overview
Drug Dependence
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by...
Birth Control Methods

