Related Experiment Video
Updated: Jun 30, 2025
Chromosome Preparation From Cultured Cells
Published on: January 28, 2014
Chromosomal abnormalities associated with fetal pleural effusion (I): General overview
1Department of Obstetrics and Gynecology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan; Institute of Clinical and Community Health Nursing, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Obstetrics and Gynecology, School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan; Department of Medical Laboratory Science and Biotechnology, College of Medical and Health Science, Asia University, Taichung, Taiwan.
Fetal pleural effusion can indicate chromosomal abnormalities. Understanding these genetic links aids in prenatal diagnosis, genetic counseling, and potential fetal therapies for expectant parents.
Area of Science:
- Perinatology
- Medical Genetics
- Fetal Medicine
Background:
- Fetal pleural effusion (FPE) is a complex condition with diverse etiologies.
- Associated conditions range from chromosomal abnormalities to infections and cardiac defects.
- Identifying the underlying cause is crucial for appropriate management and counseling.
Purpose of the Study:
- To review chromosomal abnormalities linked to fetal pleural effusion.
- To provide a resource for genetic counseling and fetal therapy decisions.
- To enhance prenatal diagnosis of FPE.
Main Methods:
- Literature review of studies on fetal pleural effusion and chromosomal abnormalities.
- Synthesis of data on genetic syndromes and their association with FPE.
- Analysis of the clinical implications for prenatal diagnosis.
Main Results:
- Specific chromosomal abnormalities are frequently associated with FPE.
- Understanding these associations aids in risk assessment.
- Genetic counseling is essential for affected pregnancies.
Conclusions:
- Chromosomal abnormalities are a significant factor in fetal pleural effusion.
- Prenatal diagnosis and genetic evaluation are critical.
- This review supports informed decision-making in fetal therapy and management.
More Related Videos
08:22A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
Published on: December 1, 2017
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Related Concept Videos
01:25Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
01:28Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
01:30Pleural Disorders: Types and Brief Description
01:23Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
01:31Respiratory System Abnormal Finding II: Palpation and Auscultation
Palpation Findings
During a respiratory assessment, palpation can reveal several vital abnormalities:
01:30Respiratory System Abnormal Finding I: Inspection and Percussion
Inspection Findings
During an inspection, several findings may suggest the presence of respiratory distress or disease. Pursed-lip breathing, where exhalation is slowed by...