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Related Experiment Video

Updated: Jun 30, 2025

Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees
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Transcutaneous osseointegration for amputees.

Andrew R Evans1, Kevin Tetsworth2, Stephen Quinnan3

  • 1Orthopedic Trauma Service, Department of Orthopedics, The Warren Alpert School of Medicine, Brown University/Rhode Island Hospital, Providence, RI.

OTA International : the Open Access Journal of Orthopaedic Trauma
|March 15, 2024
PubMed
Summary

Transcutaneous osseointegration for amputees (TOFA) offers a revolutionary prosthetic interface. Establishing TOFA programs requires specialized prostheses, multidisciplinary teams, and unique healthcare infrastructure for successful outcomes.

Keywords:
amputationamputeeorthopaedic traumaosseointegrationprosthesisrehabilitation

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Area of Science:

  • Biomedical Engineering
  • Rehabilitation Medicine
  • Prosthetics

Background:

  • Transcutaneous osseointegration for amputees (TOFA) presents a novel approach to prosthetic limb integration.
  • This technology has the potential to significantly improve the amputee-prosthesis interface across various amputation levels.
  • Current prosthetic interfaces face challenges that TOFA aims to address.

Purpose of the Study:

  • To review the emerging evidence supporting transcutaneous osseointegration for amputees.
  • To identify and discuss the challenges faced by healthcare providers in establishing TOFA programs, particularly in the United States.
  • To highlight the specialized requirements for successful TOFA implementation.

Main Methods:

  • Review of current literature on transcutaneous osseointegration in amputee care.
  • Analysis of the multidisciplinary team and specialized prosthesis requirements for TOFA.
  • Examination of healthcare infrastructure needs and care pathway considerations for TOFA programs.

Main Results:

  • Emerging evidence supports TOFA as a promising prosthetic interface.
  • Successful TOFA implementation necessitates a highly specialized prosthesis and a dedicated multidisciplinary team.
  • Significant challenges exist in establishing the necessary infrastructure and care pathways for TOFA programs in healthcare settings.

Conclusions:

  • Transcutaneous osseointegration for amputees is a developing technology with transformative potential.
  • The successful adoption of TOFA requires significant investment in specialized resources, including prosthetics and comprehensive care teams.
  • Addressing the infrastructural and logistical challenges is crucial for expanding access to TOFA in healthcare systems.