ISCEV standard for clinical pattern electroretinography (2024 update)

Area of Science:

• Ophthalmology
• Neuroscience
• Clinical Electrophysiology

Background:

• The pattern electroretinogram (PERG) assesses macular and retinal ganglion cell function.
• Previous ISCEV standards guided PERG testing protocols.

Purpose of the Study:

• To present an updated and revised ISCEV Standard for clinical PERG testing.
• To replace all earlier versions of the PERG standard.

Main Methods:

• Specifies minimum protocols for PERG stimuli and recording methods.
• Addresses evolving clinical practices and technology in electrophysiology.
• Includes updated guidance on stimulus fields and simultaneous recordings.

Main Results:

• Provides revised minimum protocols for clinical PERG testing.
• Details changes including expanded guidance on large stimulus fields and baseline drift correction.
• Ensures consistency in diagnosis and monitoring through standardized methods.

Conclusions:

• The updated ISCEV Standard promotes consistent, high-quality PERG recordings.
• Facilitates inter-laboratory comparisons and reliable diagnosis of retinal disorders.
• Reflects current clinical practices and technological advancements in electroretinography.