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Updated: Jul 10, 2026
12:18
Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth
Published on: February 9, 2012
12.4K
Development of a suitable vibration pad for renal MR elastography.
Yoshito Ishihara1, Tomokazu Numano1, Daiki Ito2
1Department of Radiological Sciences, Graduate School of Human Health Sciences, Tokyo Metropolitan University, 7-2-10, Higashiogu, Arakawa-ku, Tokyo 116-8551, Japan.
Magnetic Resonance Imaging
|March 16, 2024
Summary
A new 3D-printed Flexible Pad enhances kidney stiffness measurement using magnetic resonance elastography (MRE). This innovation improves shear wave transmission for more reliable chronic kidney disease (CKD) diagnosis.
Area of Science:
- Biomedical Engineering
- Medical Imaging
- Nephrology
Background:
- Chronic kidney disease (CKD) affects over 800 million people globally.
- Renal fibrosis, a key feature of CKD, increases kidney tissue stiffness.
- Magnetic resonance elastography (MRE) can detect tissue stiffness for CKD diagnosis.
Purpose of the Study:
- To develop a novel vibration pad for improved renal MRE.
- To enhance the transmission of shear waves for accurate stiffness measurement.
Main Methods:
- A 3D-printed "Flexible Pad" was designed and fabricated.
- The pad was positioned under participants to conform to body contours.
- Shear wave propagation and kidney shear moduli were measured in healthy volunteers.
Main Results:
- The Flexible Pad facilitated efficient transmission of coherent shear waves to deep abdominal tissues.
- Measured shear moduli for healthy kidneys were 8.95 ± 0.84 kPa (right) and 9.70 ± 0.99 kPa (left).
Conclusions:
- The developed Flexible Pad enables reliable measurement of renal shear modulus using MRE.
- This technology holds promise for improved diagnosis and monitoring of CKD.
Keywords:
Chronic kidney diseaseKidneyMR elastographyMotion encoding gradientRenal fibrosisVibration padMore Related Videos
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