Association between the early repolarization pattern and nocturnal suicide attempts.
Hiroshi Kameyama1,2, Kenichi Sugimoto3, Fumitoshi Kodaka1
1Department of Psychiatry, The Jikei University School of Medicine, Tokyo, Japan.
Neuropsychopharmacology Reports
|March 17, 2024
Summary
Early repolarization pattern (ERP) on electrocardiograms may predict nocturnal suicide attempts in mental health patients. This finding suggests ERP could serve as a biological indicator for increased nighttime suicide risk.
Area of Science:
- Cardiology
- Psychiatry
- Electrocardiography
Background:
- Recent reports link mental disorders with electrocardiographic findings.
- Early repolarization pattern (ERP) is associated with suicide attempts, ADHD, and impulsivity.
- Suicidal intent is often higher during nighttime hours.
Purpose of the Study:
- To investigate the association between ERP and nocturnal suicide attempts in patients with a history of suicide attempts.
- To determine if ERP can serve as a biological indicator for predicting nighttime suicide risk.
Main Methods:
- 43 patients with a history of suicide attempts underwent electrocardiographic examination.
- Only daytime examinations were included to account for diurnal variations.
- Multivariate analysis was used to examine the association between ERP and nocturnal suicide attempts.
Main Results:
- Patients with ERP showed a higher frequency of nocturnal suicidal behavior (76.2%) compared to those without ERP (31.8%), though not significant after Bonferroni correction.
- Multivariate analysis revealed a significant association between ERP and nocturnal suicide attempts (p=0.018).
Conclusions:
- The study found a significant association between ERP and nocturnal suicide attempts.
- ERP may function as a biological indicator for predicting nocturnal suicide attempts in at-risk populations.
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