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[Characteristics of effusive pericarditis in N'Djamena (Chad)]
D T Naïbé1,2, M H Langtar1, D G Mandi3
1Service de cardiologie du CHU la Référence Nationale, N'Djamena, Tchad.
Insights
Effusive pericarditis is a common cause of hospitalization, particularly in young adults. Tuberculosis is the leading cause in Chad, with a high mortality rate, highlighting the need for targeted interventions.
Area of Science:
- Cardiology
- Infectious Diseases
- Epidemiology
Context:
- Pericarditis is a frequent cause of hospitalization in cardiology and internal medicine.
- Effusive pericarditis presents a significant clinical challenge, particularly in resource-limited settings.
Purpose:
- To delineate the epidemiological characteristics of effusive pericarditis.
- To identify the primary etiologies and outcomes of effusive pericarditis at a tertiary care center in Chad.
Summary:
- A 3-year cross-sectional study in N'Djamena, Chad, analyzed 78 cases of effusive pericarditis.
- The predominant etiologies were tuberculosis (47%), idiopathic (21%), and HIV infection (13%).
- High in-hospital mortality (17%) was observed, with common symptoms including dyspnea and chest pain.
Impact:
- This study underscores the significant burden of effusive pericarditis in Chad, with tuberculosis as a major driver.
- Findings highlight the need for improved diagnostic and therapeutic strategies for effusive pericarditis in similar epidemiological contexts.
- The high mortality rate emphasizes the urgency for public health interventions targeting infectious causes of pericarditis.
Introduction:
Pericarditis is a commun cause of hospitalisation in cardiology and internal medicine wards.
Objective:
We aimed to describe the epidemiological profile of effusive pericarditis at the Department of cardiology of the National Referral Teaching Hospital of N'Djamena, Chad.
Methods:
We undertook a descriptive cross-sectional study from January 2017 to December 2019. Patients presenting with effusive pericarditis and who consent to participate were consecutively enrolled during the study period.
Results:
Overall, 1805 patients were hospitalized at the department of cardiology during the study period with effusive pericarditis accounting for 4.3% of all cases (n = 78). Patients' mean age was 35.84 ± 14 years, [range 16 and 73 years]. The sex ratio was 0.89. Exertional dyspnea, chest pain, poor general condition and fever were main symptoms reported in 90%, 89%, 81% and 51% of the cases respectively. Pericardial rub was found in 51% of the study patients. Eighteen patients (26%) were HIV positive and 97% of the study patients had cardiomegaly. ECG demonstrated low QRS voltage (97%) and diffuse abnormalities of repolarisation (96%). Pericardial effusion was found abundant in 57% of the cases. Etiologies of effusive pericarditis were mainly tuberculosis (47%), idiopathic (21%) and HIV infection (13%). Thirty patients (43%) benefited from pericardiocentesis. The in-hospital mortality rate of the disease was 17%.
Conclusion:
Effusive pericarditis is frequent and associated with poor outcome. Treatment depends on etiology dominated by tuberculosis in Chad.
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