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Allergic Drug Reactions01:27

Allergic Drug Reactions

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Hypersensitivities01:30

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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Cross-reactivity00:42

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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Antibody Structure01:10

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Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
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Articles linked to this work by shared authors, journal, and citation graph.

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[Consensus of Mexican experts on long-term prophylaxis in patients with hereditary angioedema in Mexico].

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)·2026
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[Frequency of signs and symptoms in the Post-COVID Syndrome of subjects partially or fully recovered from COVID-19].

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[Prevention in food allergies].

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[Food anaphylaxis].

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[Oral allergy syndrome (OAS)].

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Epidemiological and Clinical Characteristics of Hospitalized Pediatric Patients with SARS-CoV-2 Infection in Mexico City, Mexico.

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Updated: Jun 30, 2025

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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[Non-IgE-mediated food allergy].

María Isabel Rojo Gutiérrez1, Diego Ballesteros González2, Ana Karen Ortiz Durán3

  • 1Alergóloga e Inmunóloga clínica, Máster en Ciencias y Educación; Miembro de la Mesa Directiva de SLAAI; miembro activo del Colegio Mexicano de Inmunología Clínica y Alergia; Directora de Alergología en la Unidad Médica Zúrich, Ciudad de México.mi_rojo@yahoo.com.

Revista Alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)
|March 20, 2024
PubMed
Summary

Food allergies involve immune responses to food proteins, impacting the GI tract. Fecal microbiota transplantation offers an effective approach to managing these allergies by altering gut microecology.

Keywords:
Allergic proctocolitis induced by food proteinsFecal microbiotaFood allergyNon-IgE-mediated food allergyProbioticshematochezia

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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Area of Science:

  • Immunology
  • Gastroenterology
  • Microbiology

Context:

  • Food allergy is an immune response to food proteins, affecting 8% of children and 2% of adults.
  • Non-IgE-mediated food allergies primarily impact the gastrointestinal tract.
  • Gastrointestinal food allergies are categorized as IgE-mediated, non-IgE-mediated, or mixed.

Purpose:

  • To classify gastrointestinal food allergies based on pathogenesis.
  • To describe symptoms of food protein-induced allergic proctocolitis and enterocolitis syndrome.
  • To explore potential therapeutic interventions like probiotics and fecal microbiota transplantation.

Summary:

  • Food protein-induced allergic proctocolitis causes distal colon inflammation and hematochezia in neonates.
  • Food protein-induced enterocolitis syndrome, a non-IgE-mediated allergy, presents with repetitive vomiting, often triggered by shellfish in adults.
  • Atopic diseases are prevalent in patients with these food allergies.

Impact:

  • Probiotics (Lactobacillus GG) may alleviate allergic proctocolitis symptoms by modulating gut microbiota.
  • Fecal microbiota transplantation (FMT) demonstrates efficient modulation of intestinal microecology compared to probiotics or dietary changes.
  • Understanding these conditions is crucial for effective diagnosis and management of food allergies.