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The rationale for bladder washouts in children with neurogenic bladder
Gopal-Krsna Singh1, Aniruddh V Deshpande2,3,4,5, Gemma Schlegel5
1Department of Paediatrics, School of Clinical Sciences at Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.
Neurourology and Urodynamics
|March 22, 2024
Summary
Neurogenic bladder in children can lead to frequent urinary tract infections and kidney damage. Bladder washouts using electrochemically activated solutions offer a novel, non-antibiotic approach to prevent chronic bacteriuria in these high-risk patients.
Area of Science:
- Pediatric Urology
- Nephrology
- Infectious Diseases
Background:
- Children with neurogenic bladder face risks of recurrent urinary tract infections (UTIs) and kidney failure.
- Altered lower urinary tract function can lead to misdiagnosis and inappropriate treatment of UTIs.
- These patients are frequent healthcare users, susceptible to antibiotic resistance due to frequent interventions.
Purpose of the Study:
- To explore electrochemically activated solutions as a non-antibiotic prophylactic option for bladder dysfunction.
- To address chronic bacteriuria in children undergoing clean intermittent catheterization.
- To reduce the incidence of UTIs and subsequent complications in this vulnerable population.
Main Methods:
- Utilized non-antibiotic electrochemically activated solutions for bladder washouts.
- Applied the intervention in pediatric patients with neurogenic bladder and chronic bacteriuria.
- Focused on patients where clean intermittent catheterization had previously resulted in persistent bacteriuria.
Main Results:
- Electrolyzed solutions demonstrated potential as a prophylactic agent.
- This approach offers an alternative to antibiotic therapy for managing chronic bacteriuria.
- The study highlights a novel strategy for bladder dysfunction management.
Conclusions:
- Bladder washouts with electrochemically activated solutions present a promising new prophylactic strategy.
- This method may help prevent chronic bacteriuria in children with neurogenic bladder dysfunction.
- It offers a potential solution to mitigate antibiotic resistance concerns in this patient group.
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