Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colloids03:22

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...
Electrospray Ionization (ESI) Mass Spectrometry01:12

Electrospray Ionization (ESI) Mass Spectrometry

Higher molecular weight biomolecules are nonvolatile compounds that may decompose before ionizing or vaporizing during mass analysis with conventional electron impact ionization methods. Accordingly, electrospray ionization (ESI) is the favored method for vaporizing and ionizing biomolecules as it circumvents rapid fragmentation and enables the recording of mass signals for the entire biomolecule.
ESI utilizes electrical energy to transfer ions from the liquid phase of the sample into the...
Colloidal precipitates01:09

Colloidal precipitates

The high insolubility of some precipitates can result in an unfavorable relative supersaturation. This can lead to colloidal particles with a large surface-to-mass ratio, where adsorption is promoted. For instance, in the precipitation of silver chloride, silver ions are adsorbed on the surface of the colloidal particles, forming a primary layer. This layer attracts ions of opposite charge (such as nitrate ions), forming a diffuse secondary layer of adsorbed ions. This electric double layer...
Coagulation01:06

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
The Colloidal State01:29

The Colloidal State

The formation of a colloidal system is exemplified by an aqueous solution containing Cl− ions is introduced to another containing Ag+ ions, resulting in the precipitation of solid AgCl as extremely tiny crystals. Instead of settling out as a filterable precipitate, these crystals remain suspended in the liquid, showcasing a colloidal system.A colloidal system involves colloidal particles within the approximate range of 1 to 1000 nm in at least one dimension, dispersed in a medium called the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Electrospun membranes from natural polymers with Quercetin: design and characterization, antioxidant and antimicrobial activity, and potential for skin reinnervation in chronic wounds.

International journal of pharmaceutics·2025
Same author

Dual and sequential drug delivery systems with antimicrobial and bone regenerative therapeutic effects.

Journal of materials chemistry. B·2025
Same author

Alginate Microencapsulation as a Tool to Improve Biostimulant Activity Against Water Deficits.

Polymers·2025
Same author

Polycaprolactone/Doped Bioactive Glass Composite Scaffolds for Bone Regeneration.

Journal of functional biomaterials·2025
Same author

Electrospun poly(lactic acid) membranes with defined pore size to enhance cell infiltration.

Heliyon·2024
Same author

Evaluation of Gelatin-Based Poly(Ester Urethane Urea) Electrospun Fibers Using Human Mesenchymal and Neural Stem Cells.

Macromolecular bioscience·2024

Related Experiment Video

Updated: Jun 19, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.7K

Bioactive Hydroxyapatite Aerogels with Piezoelectric Particles.

Catarina Tavares1, Tânia Vieira2, Jorge C Silva2

  • 1CENIMAT|i3N, Department of Materials Science, School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.

Biomimetics (Basel, Switzerland)
|March 27, 2024
PubMed
Summary

Hydroxyapatite (HAp) aerogels with barium titanate (BT) particles show potential for bone tissue regeneration. While some concentrations were cytotoxic, lower doses suggest bioactivity and potential for hard tissue replacement.

Keywords:
aerogelbarium titanatebioactivityhydroxyapatitepiezoelectricitysolvothermal synthesis

More Related Videos

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
05:41

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

19.3K
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

3.7K

Related Experiment Videos

Last Updated: Jun 19, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.7K
Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
05:41

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

19.3K
Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering
07:14

Synthesis of Graphene-Hydroxyapatite Nanocomposites for Potential Use in Bone Tissue Engineering

Published on: July 27, 2022

3.7K

Area of Science:

  • Biomaterials Science
  • Materials Chemistry
  • Tissue Engineering

Background:

  • Open-cell hydroxyapatite (HAp) foams mimic the extracellular matrix (ECM) for hard tissue regeneration.
  • Piezoelectricity and surface charges are crucial for bone remodeling processes.

Purpose of the Study:

  • To produce and characterize HAp nanowire aerogels incorporating barium titanate (BT) particles.
  • To evaluate the physical, chemical, bioactivity, and in vitro cytotoxicity of these novel aerogels.

Main Methods:

  • Synthesis of HAp nanowire aerogels with BT particles of varying sizes.
  • Characterization of material properties using techniques like SEM/EDS.
  • In vitro cytotoxicity and bioactivity assays.

Main Results:

  • HAp nanowires were identified as AB-type carbonated hydroxyapatite.
  • Aerogels exhibited high porosity and homogeneous BT particle distribution.
  • BT particles were non-cytotoxic; aerogels showed concentration-dependent cytotoxicity, becoming non-cytotoxic at 0.5 mg/mL and below.

Conclusions:

  • The HAp/BT aerogels demonstrate potential for hard tissue regeneration applications.
  • Bioactivity assays suggest a possible calcium phosphate deposition/dissolution cycle.
  • Further investigation is needed to optimize cytotoxicity and fully elucidate bioactivity mechanisms.