Related Experiment Video
Updated: Jun 29, 2025

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Measuring the 50% Haemolytic Complement CH50 Activity of Serum
Published on: March 29, 2010
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Complement: you gutsy thing!
1Complement and Inflammation Research Section, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, USA.
Trends in Immunology
|March 27, 2024
Abstract:
Complement, traditionally perceived as a liver-derived and plasma-operative guardian against bloodborne pathogens, is increasingly recognized as a local and central player in tissue immunity. Two recent studies, by Xu et al. and Wu et al., validate this concept in the mouse gut, where extrahepatic, intestine-produced, and/or operative C3 protects against enteric infections.
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