Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...

Substance Use Disorders Affecting Sleep

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Levels of engagement among office-based opioid treatment (OBOT) patients with concurrent methamphetamine use.

The American journal on addictions·2024

Same author

Jail Characteristics and Availability of Opioid Treatment Services: Results from a Nationally Representative Survey.

The journal of behavioral health services & research·2024

Same author

Mental Health Conditions, Substance Use Disorders, and Jail Readmission in Four Rural Counties.

International journal of offender therapy and comparative criminology·2023

Same author

Naloxone Plus, Plus Some: Examining Ohio's Quick Response Teams Through the Lens of Deflection.

Journal of public health management and practice : JPHMP·2022

Same author

An Ultra-Brief 2-Item Depression Screening Tool for Correctional Populations.

Journal of correctional health care : the official journal of the National Commission on Correctional Health Care·2021

Same author

Posttraumatic stress, panic disorder, violence, and recidivism among local jail detainees.

International journal of prisoner health·2019

Search research articles

Related Experiment Video

Updated: Jun 29, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Detecting DSM-5 Opioid and Methamphetamine Use Disorders With the UNCOPE Screen.

Albert M Kopak¹, Sierra D Thomas¹, Norman G Hoffmann^2,3

¹Department of Research, UNC Health Sciences, The Mountain Area Health Education Center, Asheville, NC, USA.

Substance Use & Addiction Journal

|April 3, 2024

Summary

The UNCOPE screen accurately identifies opioid and methamphetamine use disorders in jail populations. A brief, 2-item version can efficiently detect these substance use disorders upon admission.

Keywords:

DSM-5 jail methamphetamine opioid screen

More Related Videos

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

Related Experiment Videos

Last Updated: Jun 29, 2025

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry

Published on: April 23, 2019

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs

Published on: November 8, 2024

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones

Published on: February 5, 2018

Area of Science:

Addiction Medicine
Criminal Justice Health
Psychiatry

Background:

The opioid epidemic causes record drug overdoses, particularly among criminal justice populations.
Opioid and methamphetamine use disorders are prevalent in detention centers.
Many correctional facilities lack routine screening for these substance use disorders.

Purpose of the Study:

To evaluate the UNCOPE, a 6-item screen, for detecting probable DSM-5 opioid and methamphetamine use disorders.
To identify key indicators for these specific substance use disorders.

Main Methods:

Comprehensive substance use assessments were conducted with 717 adults admitted to 4 county jails.
The UNCOPE screen's utility was examined against DSM-5 diagnoses.

Main Results:

Three positive UNCOPE responses detected 99.8% of opioid use disorder and 98.7% of methamphetamine use disorder diagnoses.
Receiver operating characteristic curves showed high accuracy (AUC 0.99 for opioid, 0.98 for methamphetamine).
Two UNCOPE items identified 100% of opioid use disorder and 99.6% of methamphetamine use disorder cases.

Conclusions:

The UNCOPE is a practical and efficient tool for identifying opioid and methamphetamine use disorders.
A 2-item UNCOPE screen can serve as an ultra-brief method for detection upon jail admission.