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Related Concept Videos

Virtual Work01:20

Virtual Work

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The principle of virtual work states that if a body is in static and dynamic equilibrium, then the sum of all the virtual work done by all external forces and couple moments for any given virtual displacement must be zero.
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Principle of Virtual Work: Problem Solving01:13

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The principle of virtual work is an essential concept in the field of mechanics and engineering. This is used to solve problems related to the equilibrium of a structure or system. It is based on the assumption that if a system is in equilibrium, the work done by all the forces during a virtual displacement is zero. This principle is applied by considering virtual displacements of the system and the corresponding work done by internal and external forces.
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Virtual Work for a System of Connected Rigid Bodies01:06

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Virtual work is a powerful method used to solve problems involving several connected rigid bodies. When the system is in equilibrium, virtual work is zero. This allows the calculation of the resulting forces when a system undergoes a virtual displacement. When attempting to analyze such a system, first, use a free-body diagram, where an independent coordinate represents the configuration of the links, and mark its deflected position resulting from the positive virtual displacement.
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Dissociative Identity Disorder01:30

Dissociative Identity Disorder

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Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...
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Visual System01:26

Visual System

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Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
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Vygotsky's Cognitive Development in Cultural Context01:22

Vygotsky's Cognitive Development in Cultural Context

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Lev Vygotsky, a pioneering Russian psychologist, developed a theory of cognitive development that centers on the influence of social and cultural factors. Unlike Jean Piaget, who emphasized the child's direct interaction with the physical world as key to development, Vygotsky argued that cognitive growth is an interpersonal process that unfolds within a cultural context. For Vygotsky, a child's learning cannot be separated from their social environment, which includes the values,...
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Creating Virtual-hand and Virtual-face Illusions to Investigate Self-representation
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The Virtual Child.

Richard J Gilbertson1,2, Sam Behjati3,4,5, Anna-Lisa Böttcher6,7

  • 1CRUK Cambridge Institute, University of Cambridge, Cambridge, United Kingdom.

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|April 4, 2024
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This summary is machine-generated.

Researchers are developing the first Virtual Child, a computer model simulating human development and cancer at the cellular level. This innovative tool aims to accelerate the discovery of effective pediatric cancer treatments, ultimately saving children's lives.

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Area of Science:

  • Computational biology
  • Developmental biology
  • Pediatric oncology

Background:

  • Childhood cancer remains a significant health challenge.
  • Current treatment development is lengthy and costly.
  • Understanding normal and cancerous human development is crucial.

Purpose of the Study:

  • To create the world's first Virtual Child, a comprehensive computer model of human development.
  • To simulate cancerous growth within the Virtual Child model.
  • To utilize the model for extensive virtual clinical trials to identify novel pediatric cancer therapies.

Main Methods:

  • Developing a cell-level computational model of human development.
  • Integrating mechanisms of cancerous development into the model.
  • Conducting in silico clinical trials on the Virtual Child to test treatment efficacy.

Main Results:

  • The Virtual Child model is under development, representing normal and cancerous human development.
  • The model will enable simulation of cancer progression and response to interventions.
  • Virtual trials will identify, predict, and prioritize potential new treatments.

Conclusions:

  • The Virtual Child represents a paradigm shift in pediatric cancer research.
  • This approach promises to accelerate the development of life-saving treatments.
  • The ultimate goal is to eliminate childhood cancer mortality.